Minions Stuart, Kevin and Bob are recruited by Scarlet Overkill, a super-villain who, alongside her inventor husband Herb, hatches a plot to take over the world.
Minions are small, yellow creatures who have existed since the beginning of time, evolving from single-celled organisms into beings who exist only to serve history’s most villainous masters. They speak their own language, Minionese, a conlang consisting of funny sounding words from Italian, Korean, and other languages.  They find great masters—including a T-Rex, a caveman, an Egyptian pharaoh, Dracula, and Napoleon,—but after accidentally killing nearly all of them with their incompetence, they decide to isolate themselves from the world and start a new life in Antarctica. By 1968, the lack of a master to serve drives them into depression, so Kevin, one fearless Minion, plans to find a new one for them by going back out into the world. Stuart—a bored, teenaged minion who is obsessed with guitars—joins him reluctantly, as does an over-enthusiastic Bob, whom Kevin only chooses because of no one else willing to volunteer.